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Showing posts with label symptoms. Show all posts
Showing posts with label symptoms. Show all posts

Marker That Indicates Breast Cancer Recurrence

Posted by admin Sunday, January 10, 2010

One of the most significant concerns of breast cancer patients is the rate at which the cancer is likely to spread. If the rate and aggressiveness with which the cancer will spread cab be determined, the aggressiveness of the chemo treatment can also be determined. Patients with a type of cancer that is less likely to spread need not be treated as aggressively as the ones with cancer that has a tendency to spread rapidly.

Breast cancer is a disease that takes a physical and emotional toll on the patient. The violent effects of chemo on the body disturbs even the strongest of individuals. Therefore, if the strength of the chemo treatment that must be administered can be determined it will be of great help to several women suffering from this devastating disease.

As a result of recent studies, researchers have been able to discover how to determine, with a certain level of accuracy, the rate at which the breast cancer cells in a particular patient is likely to spread. This is groundbreaking research because as of now there is no reliable method by which physicians can predict what cancers will spread and how rapidly they will. This makes it very difficult to determine which patients should receive aggressive chemo and which ones need not.

For patients who have been recently diagnosed with breast cancer, there is no hundred percent accurate way of predicting whether the cancer cells will return with a vengeance even after they finish treatment. If doctors are able to identify those patients who need especially aggressive chemo sessions because their cancer cells have a propensity to spread rapidly and aggressively, the right treatment can be administered at the right time to save lives. At the same time, unnecessary treatments and hardships can also be avoided by patients who do no particularly need aggressive chemo courses.

The researchers studied a group of women with cancer that had not spread to their lymph nodes and who had not received any chemo or hormonal therapy. The results that were gathered from them were then used to analyze the tumor cells and identify the specific markers that predict relapse of cancer. Studying how these genes travel give researchers a fairly accurate method of predicting what type of cancer they are dealing with, whether the cancer cells are likely to return in future and whether it will spread aggressively.

The results of the study give patients more options to decide on how they need to approach the disease.

Source:http://www.articleclick.com/Article/Marker-that-Indicates-Breast-Cancer-Recurrence/1280940

Gastric cancer

Posted by admin Tuesday, December 29, 2009

Causes, incidence, and risk factors

Several different types of cancer can occur in the stomach. The most common type is called adenocarcinoma, which starts from one of the common cell types found in the lining of the stomach. There are several types of adenocarcinoma. Because other types of gastric cancer occur much less frequently, this article focuses on adenocarcinoma of the stomach.

Adenocarcinoma of the stomach is a common cancer of the digestive tract worldwide, although it is relatively uncommon in the United States. It occurs most frequently in men over 40 years old. This form of gastric cancer is extremely common in Japan, Chile, and Iceland. The rate of most types of gastric adenocarcinoma in the United States has declined over the years. Experts think the decrease may be related to reduced intake of salted, cured, and smoked foods.

Diagnosis is often delayed because symptoms may not occur in the early stages of the disease, or because patients self-treat symptoms that may be common to other, less serious gastrointestinal disorders (bloating, gas, heartburn, and a sense of fullness).

Risk factors for gastric cancer are a family history of gastric cancer, infection, blood type A, smoking, a history of pernicious anemia, a history of chronic atrophic gastritis, a condition of decreased gastric acid, and a prior history of an adenomatous gastric polyp.

Symptoms

Abdominal pain
Breath odor
Difficulty swallowing, particularly difficulty that increases over time
Excessive belching
Excessive gas (flatus)
General decline in health
Loss of appetite
Nausea and vomiting
Premature abdominal fullness after meals
Unintentional weight loss
Vague abdominal fullness
Vomiting blood
Weakness or fatigue

Signs and tests

The following tests can help diagnose gastric cancer:

Complete blood count (CBC) to check for anemia
Esophagogastroduodenoscopy (EGD) with biopsy
Stool test to check for blood in the stools
Upper GI series

Source: http://www.healthline.com/

Vertigo : Definition, Description and Symptoms

Posted by admin Tuesday, December 15, 2009

Definition of Vertigo

Vertigo is a type of dizziness felt as a shift in a person's relationship to the normal environment (a feeling that the room is spinning is common) or a sense of movement in space.

Although dizziness and vertigo are often used interchangeably, they are not the same thing. While all vertigo is dizziness, not all dizziness is vertigo.

True vertigo, from the Latin "vertere," to turn, is a distinct, often severe form of dizziness that is a movement hallucination.

Description of Vertigo

There are four major types of dizziness -vertigo, presyncope, disequilibrium, and lightheadedness.

Most patients with true vertigo have a peripheral vestibular disorder, such as benign positional vertigo. This is usually associated with tinnitus and hearing loss.

Central disorders, such as brain stem or cerebellar lesions, tend to be more chronic but less intense than peripheral disorders and are not associated with hearing loss. Central disorders account for only 15 percent of patients with vertigo.

Vertigo is the illusion that you - or your surroundings - are moving. You may feel that you are spinning, tilting, rocking, or falling through space. You may vomit or have ringing in the ears (tinnitus). Also, your eyes may uncontrollably jerk back and forth (a condition called nystagmus).

 

Causes and Risk Factors of Vertigo

There are several causes of vertigo:

    Benign positional paroxysmal vertigo (BPPV) is a disorder of the inner ear. The cause usually is unknown, but an upper respiratory tract infection or a minor blow to the head may be responsible. This type of vertigo occurs abruptly when you move your head up and down, or when you turn over in bed. Symptoms can be distressing but they fade in a few seconds. Avoiding positions that bring this on may reduce its occurrence.

    BPPV is the commonest form of vertigo, with attacks lasting 30 to 60 seconds, typically set off when rolling over in bed, moving the head to one side or reaching for something ("top-shelf vertigo"). Sufferers can usually describe specific head movements that trigger it.

    Although BPPV often occurs for no apparent reason, it can follow an ear infection, head or ear injury, and is thought to result from the dislodgement of normal crystalline structures in the ear's balance detectors. People with BPPV are often relieved to hear that it is due to an inner ear condition and does not signify some serious disorder such as a stroke or tumor.

    Labyrinthitis refers to a variety of conditions within the inner ear. It may be associated with inflammation, an upper respiratory infection or nerve deterioration, but often occurs independently of other problems.

    Central nervous system disorders that can cause vertigo as a symptom include multiple sclerosis, epilepsy, neck injuries, certain forms of migraine, acoustic neuroma, cerebellar and brain stem tumors, and TIAS (transient ischemic attacks).

    Symptoms of Vertigo

A patient may experience severe vertigo for days or weeks. Nausea, vomiting, and involuntary eye movements are common. The condition gradually improves, but symptoms can persist for weeks or months.

Treatment of Vertigo
Treatment depends on the diagnosis. A complete medical evaluation is recommended for anyone with vertigo. This can reveal the true cause and suggest one or more solutions based upon treating the underlying disorder.

Questions To Ask Your Doctor About Vertigo
Is it true vertigo?

What is the probable cause?

Is it related to a central nervous system disorder?

How can the symptoms be controlled?

Do I need to see a specialist?

Source:http://www.healthscout.com/ency/68/462/main.html

Lung cancer : symptoms, diagnosis and treatment

Posted by admin Monday, November 23, 2009

The lungs are two large spongy organs located inside the chest cavity. Air is breathed into the trachea (windpipe) and moves down two tubes called bronchi, each going to a lung. These tubes divide into bronchioles and then into tiny air sacs called alveoli. Lung cancers usually start in the cells lining the airways. There are different types of lung cancer, depending on which cells are affected.
Over 1,400 Victorians are diagnosed with lung cancer every year. Lung cancer occurs most often in adults between the ages of 40 and 70 who have smoked cigarettes for at least 20 years. We do not know the cause in all cases; however, up to nine out of 10 lung cancers are caused by smoking. Lung cancer is the most common cause of death from cancer in Australia.

Different types of lung cancer
A cancer that starts in the cells lining an organ is known as a carcinoma. There are different typesc of lung cancer, depending on which cells are affected. The two main types are:

Small cell carcinoma or ‘oat cell carcinoma’, named after its cell shape. Around 15 per cent of lung cancers are small cell carcinomas. This type of cancer spreads early and shows few early symptoms.

Non-small cell carcinoma – these cancers affect the cells that line the main bronchi.

Different types of non-small cell cancer
Some of the different types of non-small cell cancer include:

Squamous cell carcinoma is generally discovered earlier than other lung cancers and has the best outcome after treatment

Adenocarcinoma – is now the most common type in both males and females; the reason for the increasing incidence may be related to changing patterns of smoking including filtered cigarettes

Large cell carcinoma

Bronchiolo-alveolar cell carcinoma.

Sometimes it is not possible to tell which type someone has. This is because, when the cells are looked at under a microscope, they are not developed enough.
Symptoms
Common symptoms of lung cancer include:

Persistent cough and/or new or changed wheeze
Breathlessness
Blood-streaked phlegm
Pains in the chest
Recurring pneumonia or chest infections
Recurring bronchitis
Unexplained weight loss.

Diagnosis
Lung cancer is diagnosed using a number of tests, which may include:

Chest x-rays – cancers as small as one centimetre can be spotted on x-rays.

Sputum cytology – a sample of sputum (phlegm) is examined under a microscope to check for abnormal cells.

Bronchoscopy – a flexible tube is inserted through the mouth or nose and down the trachea, allowing the doctor to look at the lung tissue and take a small sample of tissue and phlegm.

Fine needle aspiration – a small sample of tissue is removed using a needle inserted through the chest wall.

Mediastinoscopy – a flexible tube is inserted into a cut in the neck and down to the lymph nodes to check for cancer cells in the lymph nodes.

Video-assisted thoracoscopic surgery – instruments similar to bronchoscopes are inserted into the chest wall under general anaesthetic and tissue samples may be taken.

Computed tomography (CT) scan – a specialised x-ray taken from many different angles, to build a three-dimensional picture of your body.

Fluoro-Deoxy Glucose (FDG) Positron Emission Tomography (PET) Scan – used in diagnosis and staging of lung cancer. This test involves having an injection of a small amount of radioactive material. Using the signals from this radioactive injection, a scanner can build up a picture of the body.

Other tests – including bone scans, to see if the cancer has spread to other parts of the body.

Treatment
Lung cancer is categorised into stages according to its spread. This helps the doctors to decide on appropriate treatments. Treatment options include:

Surgery – to remove the affected part of the lung (lobectomy) or an entire lung (pneumonectomy). This offers the best chance of cure if the cancer has not spread beyond the lungs.

Chemotherapy – anti-cancer drugs are given to stop cancer cells from multiplying. This treatment is most effective for small cell carcinoma.

Radiotherapy – the use of x-rays to target and kill cancer cells. Radiotherapy may be used against some early stage lung cancers and to stop cancer in the lymph nodes from spreading further. Prophylactic brain radiotherapy is often offered to people with small cell lung cancer to reduce the risk of their lung cancer spreading to their brain.

Multimodality therapy – for some people, several treatments used together give the best results.

Targeted therapy – use of small molecules, often in tablet form, that may be used after chemotherapy.

Clinical trials – participation in a clinical trial that investigates the safety and effectiveness of novel drugs may be offered.

As with most cancers, the results are best if the cancer is diagnosed in its earliest stages. However, some lung cancers aren’t diagnosed until they are quite advanced. Treatment may then be limited to easing the symptoms and can include:

Radiotherapy and chemotherapy – to contain the cancer.

Medication – including pain relievers.

Surgery – to remove cancers that are blocking main airways or to seal bleeding blood vessels.

Quit smoking programs – people diagnosed with cancer have seen benefits ranging from increased longevity (length of life) and improved quality of life, depending on their disease status, once they quit smoking.

Source:http://www.betterhealth.vic.gov.au/

Brain Cancer Symptoms

Posted by admin Tuesday, November 17, 2009 0 comments

Not all brain tumors cause symptoms, and some (such as tumors of the pituitary gland) are found mainly after death. The symptoms of brain tumors are numerous and not specific to brain tumors, meaning they can be caused by many other illnesses as well. The only way to know for sure what is causing the symptoms is to undergo diagnostic testing.

The symptoms are caused by the tumor pressing on or encroaching on other parts of your brain and keeping them from functioning normally.

Some symptoms are caused by swelling in the brain caused by the tumor or surrounding inflammation.

The symptoms of primary and metastatic brain cancers are similar.

The following symptoms are most common:

Headache
Weakness
Clumsiness
Difficulty walking
Seizures

Other nonspecific symptoms and signs include the following:

Altered mental status - Changes in concentration, memory, attention, or alertness
Nausea, vomiting - Especially early in the morning
Abnormalities in vision
Difficulty with speech
Gradual changes in intellectual or emotional capacity

In many people, the onset of these symptoms is very gradual and may be missed by both the person with the brain tumor and the family. Occasionally, however, these symptoms appear more rapidly. In some instances, the person acts as if he or she is having stroke.

Brain Cancer Symptoms: When to Seek Medical Care

See your health care provider right away if you have any of the following symptoms:

Unexplained, persistent vomiting
Double vision or unexplained blurring of vision, especially on only one side
Lethargy or increased sleepiness
New seizures
New pattern or type of headaches

Although headaches are thought to be a common symptom of brain cancer, they may not occur until late in the progression of the disease. If any significant change in your headache pattern occurs, your health care provider may suggest that you go the hospital.

If you have a known brain tumor, any new symptoms or relatively sudden or rapid worsening of symptoms warrants a trip to the nearest hospital emergency department. Be on the lookout for the following new symptoms:

Seizures
Changes in mental status, such as excessive sleepiness, memory problems, or inability to concentrate
Visual changes or other sensory problems
Difficulty with speech or in expressing yourself
Changes in behavior or personality
Clumsiness or difficulty walking
Nausea or vomiting (especially in middle-aged or older people)
Sudden onset of fever, especially after chemotherapy.

Source:http://www.webmd.com/ 

Breast Cancer : Signs and Symptoms

Posted by admin Friday, November 6, 2009 0 comments

Breast cancer begins with abnormal cells developing in breast tissue. It can be confined to the breast or may spread beyond your breast or into other parts of your body. The most common type of breast cancer begins in the ducts designed to carry milk to the nipple. But cancer also may occur in the small sacs that produce milk, called lobules, or in other breast tissue. Breast cancer varies widely and the treatment options are selected to match your individual needs.

Breast cancer may occur in several different forms, such as the five types below:

  • Breast Cancer in Situ, DCIS and LCIS -- Many breast cancers detected early, typically by mammography, are classified as breast cancer in situ or noninvasive cancer. These early cell changes may develop into invasive breast cancer. Two types of breast cancer in situ are:

    • DCIS (ductal carcinoma in situ) means that abnormal cells are found only in the lining of a milk duct of the breast. These abnormal cells haven't spread outside the duct. There are several types of DCIS. If not removed, some may change over time and become invasive cancers, while others may not. DCIS is sometimes call intraductal carcinoma.

    • LCIS (lobular carcinoma in situ) means that abnormal cells are found in the lining of a milk lobule. Although LCIS is not considered to be actual breast cancer at this noninvasive stage, it is a warning sign of an increased risk of developing invasive cancer. LCIS sometimes is found in a biopsy for another lump or unusual change detected on a mammogram.

  • Invasive Breast Cancer -- These cancer cells form in the ducts or the milk lobules and spread to the breast tissue around them. Tumors can be found during a breast exam or through screening, such as a mammogram. The size of the tumor, what it looks like under the microscope and whether it has spread to the lymph nodes determines the severity of the cancer, the therapies and the difference treatments will make.

  • Metastatic Breast Cancer -- Metastatic cancer begins in the breast, but spreads outside the breast through the blood or lymph system to other organs. Women usually develop metastatic disease in the months or years following the diagnosis of breast cancer. This cancer most commonly spreads beyond the breast to a patient's bones, lung, liver and brain.

  • Locally Advanced Breast Cancer -- Inflammatory breast cancer is a rare but very serious and aggressive type of breast cancer. The breast may look red and feel warm. A patient may see ridges, welts or hives on the breast or its skin may look wrinkled. It is sometimes misdiagnosed as an infection.

  • Recurrent Breast Cancer -- Recurrent disease means that the cancer has come back or recurred after treatment. It may come back in the breast, in the soft tissues of the chest or chest wall, or in another part of the body.

Symptoms

Early breast cancer usually doesn't cause pain. In fact, when breast cancer first develops, there may be no symptoms at all. But as the cancer grows, it may cause changes that you should watch for:

- A lump or thickening in or near the breast or in the underarm area

- A change in the size or shape of the breast

- Nipple discharge or tenderness, or the nipple pulled back (inverted) into the breast

- Ridges or pitting of the breast, making the skin look like the skin of an orange

- A change in the look or feel of the skin of the breast, areola or nipple such as warmth, swelling,  redness or scaliness.

Source:http://www.ucsfhealth.org/

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